- Checkpoint Mutants
- mad2∆
- bub2∆
- mad2∆ bub2∆
- cdc20-ts mad2∆
- cdc20-ts bub2∆
- WT in nocodazole
- mad2∆ in nocodazole
- mad2∆ GAL-TEM1 in nocodazole
- mad2∆ pds1∆ in nocodazole
- bub2∆ in nocodazole
- bub2∆ pds1∆ in nocodazole
- bub2∆ mad2∆ in nocodazole
- pds1∆ in nocodazole
- net1-ts in nocodazole
net1-ts in nocodazole
debug: ,
test user =
test db =
Simulation:
Change of parameters: kasrent=1, kasrentp=0.005, ksspn=0.
Arrest: Mitotic exit at t=250.8 min.
Experiments:
Visintin, R., Hwang, E.S., Amon, A. (1999). Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus. Nature 398:818-823.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: This mutant cannot be arrested in nocodazole, Clb2 is degraded.
Comments:
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